Name: Farouk Olubajo

 

Theme: Congenital Adrenal Hyperplasia (Clinical Chemistry)

 

OPTION LIST

 

A

11β-Hydroxylase deficiency

I

Hypernatreamia with Hyperkalaemia

B

17-Hydroxyprogesterone

J

Hypernatreamia with Hypokalaemia

C

17α-Hydroxylase deficiency

K

Hyponatreamia with Hypokalaemia

D

21-Hydroxylase Deficiency

L

Hyponatreamia with Hyperkalaemia

E

Aldosterone

M

Normal ACTH levels

F

Chromosome 6

N

Raised ACTH

G

Cortisol

O

Reduced Cortisol

H

Deoxycortisol

P

Pregnanetriol

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. The commonest enzyme deficiency seen in CAH

 

 

2. Levels of this steroid are raised in the serum of CAH patients

 

 

3. Increased levels are seen in the urine of CAH patients

 

 

4. The sodium and potassium states seen in some CAH patients

 

 

5. A doctor suspecting his patient is suffering from CAH has just received some results that proves otherwise.

 

 

ANSWERS

1. D

2. B

3. P

4. L

5. M